Sunday, May 15, 2011

Breech presentation and ECV

Breech presentation
• 22% of births prior to 28 weeks' gestation
• 7% of births at 32 weeks' gestation
• 1-3% of births at term
Lie stable at 36 weeks

Types of breeches
• Frank breech (50-70%) - Hips flexed, knees extended
• Complete breech (5-10%) - Hips flexed, knees flexed
• Footling or incomplete (10-30%) - One or both hips extended, foot presenting

Aetiology /Associations
Uterine/placenta
• Uterine Anomalies ( bicornuate, Septate)
• lax uterus (multi parity)
• uterine Fibroids
• Placenta previa
• Polyhydroamnios
• Oligohydroamnios
Fetus
• Multiple praganancy
• Fetal congenital anomalies (hydrocephalus, anancaphaly)
• Intrauterine Death
• Prematurity

Management
• ECV
• If fail decide on mode of delivery ie. Vaginal Delivery Vs LSCS

Vaginal breech delivery Vs planned LSCS

Planned LSCS carries a reduced perinatal mortality compared with planned vaginal birth.


Favorable for Vaginal Delivery Unfavorable for vaginal breech birth
Good pelvimetry ( previous delivery of normal sized infant) Nulliparous / Clinically inadequate pelvis
EFW 2 – 3.8 kg 2kg >EFW >3.8 kg
Extended Breech/flexed Footling
Flexed Neck Hyper extended Neck
Normal liquor volume Oligohydroamnios/ polyhydroamnios
Previous Caserian section
Other contraindications to vaginal birth (e.g., placenta praevia, compromised fetal condition)


Intrapartum Management of vaginal breech Delivary
 Maternal position : dorsal or lithotomy position
 Stage 1 :
• VE ; exclude cord presentation, cord prolapsed (common in flexed breech)
• Adequate analgesia
 Stage2:
• episiotomy to facilitate delivery of aftercoming head
• delivery of the leg : pinnard’s maneuver
• delivery of the shoulders : the Lovset maneuver
• delivery of head may be delivered with forceps, the Mauriceau-Smellie-Veit maneuver.

 If conservative methods fail, symphysiotomy or caesarean section should be performed.

Complications of vaginal breech delivery
• Fetal hypoxia ;
 cord prolapsed,
 placental separation before delivery of head,
 compression of umbilical cord,
 premature inspiration of mucus obstructing the airways

• intracranial hemorrhage: rapid decent of the after coming head causing sudden compression followed by decompression leading to tentorial tear and ICB
• Entrapment of after coming head
• Trauma to the baby: Femur #, hip dislocation, damage to viscera, shoulder dystocia with humerus #



External cephalic version (ECV)
External cephalic version (ECV) is the manipulation of the fetus through the maternal abdomen to a cephalic presentation.
An overall success rate
40% for nulliparous,
60% for multiparous
Spontaneous reversion to breech presentation after successful ECV occurs in less than 5%


When should ECV be offered?

36 weeks in nulliparous women
from 37 weeks in multiparous women.


Contraindications for ECV

• antepartum haemorrhage within the last 7 days
• proteinuric pre-eclampsia
• major uterine anomaly
• scarred uterus
• placenta previa
• ruptured membranes
• oligohydramnios
• multiple pregnancy (except delivery of second twin
• IUGR
• major fetal anomalies
• abnormal cardiotocography
• unstable lie.







Complications

• placental abruption
• fetomaternal transfusion (rhesus sensitization of mother)
• uterine rupture /scar dehiscence
• cord prolapse,
• rupture of membranes
• Amniotic fluid embolism
• stillbirth
• transient abnormal fetal heart rate changes
• emergency cesarean delivery
Prerequisites for ECV/ procedure :

1. informed consent include

2. an ultrasound examination : to confirm fetal and placental position /liquor volume

3. CTG – Reactive CTG

4. Check rhesus status (anti-D immunoglobulin is normally offered to rhesus-negative women)

5. Facilities for rapid progression to LSCS, if necessary

 Fasting 4-6 hours

 beta-adrenergic receptor agonist (eg, salbutamol or terbutaline) to relax the uterus

 apply powder (eg, cornstarch) over the patient's abdomen

 breech is disengaged from the pelvis

 version performed in a way that it favors flexion

Maximum 3 attempts


Post ECV
• CTG for at least 30 mins
• Check for PV bleeding or loss of liquor
• If rhesus negative, give anti D
• If unsuccessful repeat after one week or elective LSCS

Wednesday, December 22, 2010

MENINGITIS

Meningitis

Causes:

Infectious

Non Infectious

Viral

§ Commonest cause

§ Usually benign and self-limiting

§ Complete recovery w/o specific Rx is the norm.

§ Common organisms: echoviruses, mumps. Less commonly HSV & zoster, coxsackie

Bacterial – high mortality & morbidity

Fungal

  • malignancies,
  • autoimmune diseases eg. SLE
  • drugs (NSAIDS, trimethoprim)

Causes of bacterial meningitis by population groups:

Neonatal – 3months

1. Group B strep

2. Gram negative bacilli (E coli, proteus)

3. Listeria monocytogenes

Pre-school child

1. H. influenzae

2. N. meningitides

3. Strep. Pneumoniae

4. M. TB

Older child / Adults

1. N. Meningitidis

2. Strep. Pneumoniae

3. M. TB

Elderly / DM/ debilitated

1. Strep. Pneumoniae

2. N. Meningitidis

3. H. influenzae

4. L. monocytogenes

5. M. TB

Immuno-compromised

1. Strep. Pneumoniae

2. N. Meningitidis

3. H. influenzae

4. L. monocytogenes

5. C. Neoformans

6. Toxoplasma gondii

7. S. aureus

§ Meningococcus: Spread by air-borne route. May result in meningococcaemia.

~ Cxs of meningococcaemia: meningitis, purpuric rash, shock, DIVC, renal failure, peripheral gangrene, arthritis (rxtive or septic), pericarditis (rxtive or septic)

§ H. influenzae: a/w ottitis media

§ Pneumococcus: a/w ottitis media and pneumonia, esp in elderly, alcoholics & immunocompromised.

§ TB: chronic or acute on chronic, a/w chronic headache, isolated CN6 palsy due to ­ICP, and S/S of TB eg fever, nightsweats.

Risk factors:

Environment

Overcrowded closed communities, schools, day care centres

Head injury

skull #, cranial or spine surgery

Septic site

pneumonia, mastoiditis, sinusitis, OM

Host

Complement or antibody deficiency

Immunosuppression (CA, AIDS, hyposplenism, sickle-cell dz, hypogammaglobinaemia, DM

Foreign body

§ CSF shunt/ VP shunt (prone to staph. Meningitis)

Pathophysiology

Meningeal infection followed by bacteriemia

Host response to infection

Release of inflammatory mediators/ activated leucocytes

Endothelial damage

Cerebral edema/ raised ICP/reduced cerebral blood flow

DDx:

1. Any acute infections eg malaria

2. Local infections causing neck stiffness

3. Encephalitis

4. Subarachnoid hemorrhage

S/S:

Meningism

§ Headache

§ Photophobia

§ Neck stiffness

§ Kernig’s sign

§ Brudzinski’s sign (hip flexion on flexion of neck)

§ Opisthotonus

­ ICP

§ Headache

§ Vomiting

§ Irritability

§ Drowsiness

§ ¯consciousness/coma

§ Focal neuro signs

§ Fits

§ Bulging of fontanelle

§ Cushing’s reflex: ­BP & ¯pulse

§ Irregular respiration

§ Papilloedema

Septicaemia

§ Malaise

§ Fever

§ Rash – petechiae/purpura suggests meningiococcus.

§ DIC

§ ¯BP, ­pulse, tachypnoea

§ Arthritis

§ Odd behaviour

ComplicationS

Acute

chronic

· Seizures

· Cerebral herniation

· Increase in ICP

· Cranial nv palsies

· Subdural effusions ( H.influenza/strep.pneumonia)

· Thrombosis of subdural sinuses

· SIADH

· Waterhouse Frederickson syndrome

· Neurological deficit

· Deafness (damage to cochlear hair cells)

· Aphasia

· Ocular palsies

· Cerebral palsy

· Mental retardation

· Brain abscess

· Hydrocephalus/microcaphaly

· Epilepsy

· Diabetes insipidus

Investigations:

Blood

Full Blood Count

leukocytosis

Blood C/S

find the specific organism

Acute Phase Reactants (CRP/ESR)

BUSE/ creatinine

SIADH

Random Blood Glucose

for CSF glucose result interpretation

DIVC screen

Especially if meningococcaemia is suspected

LFT

Urine

Urine

UFEME

UTI

Urine C/S

Lumbar puncture

CSF

§ Exclude ­ ICP by CT head, fundoscopy & clinical signs.

§ Tubes

  1. Cell count, cytospin for cell and differential count
  2. Protein & glucose
  3. Microbiology – gram stain, C&S, AFB smear, TB culture, Indian ink stain, fungal culture

Cryptococcal antigen, bacterial antigens (S. pneumonia, N. meningitides, H. influenzae, GBS)

Latex agglutination for bacterial antigens

PCR ( herpes simplex)

CT head

Indications for CT scan in Meningitis

(Mainly useful to detect complications)

- Prolonged depression of consciousness

- Prolonged focal or late seizures

- Focal neurological abnormalities

- Enlarging head circumference

- Suspicious of subdural effusion or empyema

Exclude ­ICP (eg cerebral abscess, head injury, brain tumour) pre-LP.

Cerebral odema

Hemorrhage

Typical site of virus

CXR

If susupected TB

Contra indication for lumbar puncture

  • GCS<= 8
  • Cardiorespiratory instability
  • Increased in ICP

- Coma

- High BP

- Reduced HR

- Papilodema

- Tense fontanelle

  • Focal neurological signs
  • Caogulopathy
  • Thrombocytopenia
  • Local infections at the site of LP

Typical CSF in meningitis

Normal

Pyogenic

TB

Viral (‘aseptic’)

Appearance

clear

Turbid

Fibrin web forms on standing

Clear

Predominant cell

Neutrophils

Lymphocytes

Lymphocytes

Cell count/ mm3

0-5/mm3

90-1000+

10-1000

50-1000

Glucose

> 50% blood

¯ (< 1/2 plasma)

¯ (< 1/2 plasma)

N (> 1/2 plasma)

Protein (g/L)

0.15-0.4

­ (>1.5)

­ (1-5)

N (<1)

Culture / smear

Positive

Usually not seen

Negative

Treatment:

§ Monitoring: BP, pulse, RR, temp, SpO2, conscious level

§ Supplemental O2

§ ABx if bacterial (see below)

§ Antipyretics and antiemetics

§ Corticosteroids for ­ICP (controversial): 0.15mg/kg dexamethasone

Viral

§ Supportive treatment

§ Completer recovery without specific therapy is the norm.

Bacterial

§ IV penicillin stat on suspicion of bacterial meningitis

§ Modify ABx regimen according to CSF invx results

Meningococcal

Benzyl penicillin (2.4g/4hr slow IV)

Pneumococcal

Ceftriaxone (2g/12 hrly IV)

H. influenzae

Ceftriaxone

GBS/ Gram negative bacilli

Ceftriaxone + Gentamicin + ampicillin (50mg/kg/6 hr IV)

L. monocytogenes

Gentamicin + ampicillin

M TB

Pyrazinamide, isoniazid, rifampicin, ethambutol 6-12 mths

C. neoformans

Amphotericin + flucytosine

§ Treatment for pyogenic meningitis of unknown cause

Neonate

Ampicillin + Ceftriaxone or gentamicin

Infant

Ampicillin + Ceftriaxone

Pre-school child

Ceftriaxone

Older child / adults

Penicillin G (400K units/kg/day) + Ceftriaxone

Elderly (>50YO)

Ampicillin + Ceftriaxone

§ Prophylaxis for close contacts--meningococcus:

~ Children: 2 days of oral rifampicin (3-12mths 5mg/kg 12 hrly; >1yr 10 mg/kg 12 hrly)

~ Adults: single dose of 500mg ciprofloxacin OR rifampicin 600mg 12 hrly for 2 days.

§ Vaccination: available for groups A & C meningococci, but not group B.